Recent studies on the Mediterranean herb Cistus incanus (rock rose) provide some interesting comparisons. Thus a polyphenol-rich Cistus extract showed similar anti-IV activities to those described in this report, suggesting a similar mode of action [18]. The mechanism of Cistus anti-viral activity was not elucidated however, so a comparative study of these two extracts could be useful and provide interesting implications for the design of effective anti-IV compounds.

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